the last few years the federal government has established more stringent
regulations on the use of estrogen products.
addition, the cost of these products has steadily risen to the level
that is very expensive to treat large breed dogs.
product gives the pet owner an alternative to estrogen therapy.
Initially, it may be given concurrently as the dosage of estrogen
from one to three times daily. Usually the dosage can be reduced
to a daily dosage after 4-5 days.